To meet universal consumer expectations for skin beauty, Silab tapped into the properties of alfalfa (Medicago sativa), also called lucerne, a plant grown in much of the world for both its nutritional qualities and medicinal properties. The result is Includium, a multifunctional natural active ingredient that stimulates biological pathways essential to epidermal and dermal functionalities.
The French manufacturer of natural cosmetic active ingredients has strived to meet consumers’ common expectations in terms of skin beauty. To sketch the outline of this universal beauty, Silab identified the main skin characteristics of consumers around the world based on their ethnicity, gender and age.
Addressing universal demands
This study made it possible to identify three main expectations:
a beautiful skin quality, characterized by skin hydration and fine skin texture for a smoothed microrelief;
an even and radiant complexion, free from spots related to post-inflammatory scars and skin aging;
reduced signs of aging thanks to firmer skin and faded wrinkles.
And Silab claims to have found in alfalfa what it takes to satisfy these demands. To develop the new multifunctional patented active ingredient, the company has used the seeds of alfalfa, sourced from selected certified organic farms in France, to extract their galactomannans and create Inclusium [1], an active ingredient offering hydra-smoothing and complexion perfecting benefits.
Stimulation of key skin functions
Silab leveraged its expertise in tissue engineering and in transcriptomics to explore the transversal activity spectrum of Inclusium on the biological pathways essential for epidermal and dermal functions.
A large-scale exploratory study established that Inclusium stimulates epidermal functionalities by modulating the biological pathways related to the physical and water barrier, the immune barrier, and the anchoring of the epidermis to the dermis. Furthermore, according to Sliab, it reinforces the dermal matrix quality by boosting the synthesis of collagen I and reducing the synthesis of MMP-1.
Five clinical studies
The efficacy of Inclusium has been demonstrated on various panels, including mixed gender groups with young and mature, Caucasian, Asian, Latin-American, and Afro-American panels. Five clinical studies were therefore conducted, showing a hydra-smoothing, complexion-perfecting and anti-wrinkle effect as of 7 days of application.
Available in aqueous solution, Inclusium is recommended at a dose of 0.5 to 2.5%. The patented ingredient complies with biodiversity regulations and has a natural origin content of 99.2% (ISO 16128). It complies with international cosmetics regulations (Europe, USA, China, Japan, etc.).
