Mibelle Biochemistry has developed a holistic solution to increase NAD+ levels in the skin through cosmetic applications.
NAD+ is the oxidized form of Nicotinamide adenine dinucleotide (NAD), a coenzyme central to metabolism. NAD+ plays a crucial role in various cellular processes and has received significant attention in anti-aging supplements. “However, the use of NAD+ in cosmetics failed so far, as the molecule has a very poor stability in formulations and cannot be taken up into skin cells,” said Mibelle in statement.
To overcome this hurdle, the Swiss manufacturer has created RejuveNAD , a natural active ingredient that stimulates the endogenous regeneration of NAD+ by activating the enzyme NAMPT (nicotinamide phosphoribosyltransferase, formerly known as pre-B-cell colony-enhancing factor 1).
According to Mibelle, RejuveNAD “naturally boosts the longevity molecule NAD+ to optimize cellular processes.” The new active ingredient is sourced from sustainably cultivated sunflower sprouts through indoor farming.
Five hallmarks of skin aging
Clinical studies show that RejuveNAD can counteract at least five hallmarks of aging in the skin simultaneously: mitochondrial dysfunction, cellular senescence, loss of proteostasis, epigenetic alteration and genomic instability.
As a result, according to Mibelle, the skin looks eight years younger in just 42 days.